期刊简介
本刊为西南医科大学主办，经国家新闻出版署批准，向国内外公开发行的综合性医学学术期刊，其前身为《泸医资料》，创办于1973年。本刊自创办以来，得到社会各界及学院各级领导的大力支持，办刊条件和办刊水平都有较大提高。
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首页>西南医科大学学报杂志
- 杂志名称：西南医科大学学报杂志
- 主管单位：四川省教育厅
- 主办单位：西南医科大学
- 国际刊号：2096-3351
- 国内刊号：51-1772/R
- 出版周期：双月刊
期刊荣誉：全区优秀学报三等奖期刊收录：万方收录(中), 上海图书馆馆藏, 国家图书馆馆藏, 知网收录(中), 维普收录(中)
C-反应蛋白:炎性标记物抑或是动脉粥样硬化血栓形成的参与者
李蓉；任美萍
关键词：反应蛋白, 炎性标记物, 动脉粥样硬化, 血栓形成, 参与者, Development, atherosclerotic plaque, CRP, blood Coagulation, atherosclerosis, understanding, Strategy, Studies, however, focuses, Complex, better, plays, human, cells
摘要：C-reactive protein (CRP) was traditionally considered a biomarker of inflammation,however,recent studies have proved that CRP exerts prothrombotic effects on vascular cells and plays a critical role in atherothrombosis.CRP increases the risk of ischemic vascular events,for example,myocardial infarction.CRP has been detected in atherosclerotic lesions in human coronary arteries [1-5].Although CRP has been argued to be involved in the development of atherosclerotic plaque size [6-8],it is surely correlated with activating the blood coagulation system and increasing the risk of thrombosis.The present review focuses on the pivotal role of CRP in trigger of atherosclerosis,stimulation of prothrombetic factor and activation of platelets as well as subsequent development of atherothrombosis.A better understanding of each step involved in this complex process might lead to a new therapeutic strategy to manage patients with CRP-linked atherothrombosis.
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